Why the study?
Assessment of left ventricular perfusion and metabolic state using MIBI and BMIPP scintigraphy may help develop predictors of cardiac resynchronization therapy efficacy in DCM patients.
Does myocardial perfusion-metabolic scintigraphy with MIBI and BMIPP predict the efficacy of cardiac resynchronization therapy in patients with dilated cardiomyopathy?
Observational (n=51)
Does myocardial perfusion-metabolic scintigraphy with MIBI and BMIPP predict the efficacy of cardiac resynchronization therapy in patients with dilated cardiomyopathy?
Myocardial perfusion-metabolic scintigraphy with MIBI and BMIPP can identify perfusion and metabolic defects that predict response to cardiac resynchronization therapy in patients with dilated cardiomyopathy.
The objectiveof this study is to assess perfusion and metabolic state of the left ventricular in patients with dilated cardiomyopathy (DCM) using scintigraphy with MIBI and BMIPP, as well as to develop the predictors of efficacy of cardiac resynchronization therapy (CRT). The study included 51 patients with DCM who underwent CRT. Correlation between the values of LV ESV after CRT and preoperative perfusion and metabolic defects sizes was detected. "Responders" and "non-responders" groups were significantly different from the perfusion and metabolic defects sizes. Myocardial perfusion-metabolic scintigraphy can be used as additional criteria for the selection of patients for CRT.
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Zavadovsky et al. (2015) conducted an observational in Dilated cardiomyopathy (n=51). Myocardial perfusion-metabolic scintigraphy with MIBI and BMIPP was evaluated on Correlation between left ventricular end-systolic volume after CRT and preoperative perfusion and metabolic defects sizes.
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