Key result
Discrete Multiphysics modeling links blood flow and material stiffness to stent deformation at structural nodes.
Why the study?
The mechanical deformation of coronary stents and their interaction with blood flow dynamics influence stent performance and risk of vascular injury or re-stenosis.
A Discrete Multiphysics modeling approach can predict the risk of coronary stent fracture after deployment by analyzing the relationship between elastic forces in the stent and pressure forces in the fluid.
May inform stent design optimization; leaves open clinical translation without prospective validation.
Stenting is a common method for treating atherosclerosis. A metal or polymer stent is deployed to open the stenosed artery or vein. After the stent is deployed, the blood flow dynamics influence the mechanics by compressing and expanding the structure. If the stent does not respond properly to the resulting stress, vascular wall injury or re-stenosis can occur. In this work, a Discrete Multiphysics modelling approach is used to study the mechanical deformation of the coronary stent and its relationship with the blood flow dynamics. The major parameters responsible for deforming the stent are sorted in terms of dimensionless numbers and a relationship between the elastic forces in the stent and pressure forces in the fluid is established. The blood flow and the stiffness of the stent material contribute significantly to the stent deformation and affect its rate of deformation. The stress distribution in the stent is not uniform with the higher stresses occurring at the nodes of the structure. From the relationship (correlation) between the elastic force and the pressure force, depending on the type of material used for the stent, the model can be used to predict whether the stent is at risk of fracture or not after deployment.
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Mohammed et al. (2021) studied Coronary artery disease. Discrete Multiphysics (DMP) modeling of coronary stent was evaluated on Mechanical deformation and stress distribution of the coronary stent. A Discrete Multiphysics model demonstrated that blood flow and stent material stiffness significantly contribute to stent deformation, with higher stresses occurring at the nodes of the structure.
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