Key result
Noninvasive pressure-strain loop parameters predict hypertension with global work index showing ~98% specificity.
Why the study?
The value of the noninvasive pressure-strain loop technique for assessing left ventricular myocardial work in patients with essential hypertension was investigated.
Does the noninvasive pressure-strain loop (PSL) technique accurately assess left ventricular myocardial work in patients with essential hypertension compared to healthy adults?
Observational (n=100)
Does the noninvasive pressure-strain loop (PSL) technique accurately assess left ventricular myocardial work in patients with essential hypertension compared to healthy adults?
The noninvasive pressure-strain loop technique can effectively assess left ventricular myocardial work in patients with essential hypertension, with GWI and GCW showing high diagnostic specificity and sensitivity.
OBJECTIVE: To investigate the value of the noninvasive pressure-strain loop (PSL) technique for assessing left ventricular myocardial work done in patients with essential hypertension. METHODS: Prospectively, 60 patients with hypertension visiting the hospital from August 2020 to July 2021 were collected and divided into the mild hypertension group (SBP 140-159 mmHg, 35 cases) and the moderate-to-severe hypertension group (SBP ≥160 mmHg, 25 cases). Another 40 cases of healthy adults were collected as the control group. The differences in the global long-axis strain (GLS) and peak strain dispersion (PSD) of the left ventricle, global work index (GWI), global constructive work (GCW), global wasted work (GWW), and global work efficiency (GWE) were compared among the three groups. The receiver operating characteristic curve was used to evaluate the PSD, GWI, GCW, and GWW. The myocardial work index (MWI) and MWI percentages in the apical, middle, and basal segments of the heart were also compared among the groups. RESULTS: = 1.559 and 5.849, respectively, p > .05). (2) The GWI had the highest specificity (97.5%) and the GCW the highest sensitivity (95%) in predicting hypertension. The percentage of apical MWI gradually increased (F = 11.230, p < .05) and the percentage of basal MWI gradually decreased (F = 10.665, p < .05) from the control group to the mild hypertension group to the moderate-to-severe hypertension group; there was no significant difference in the percentage of mid-MWI (F = 0.593, p > .05). CONCLUSIONS: The noninvasive PSL technique could be used to assess myocardial work done in patients with essential hypertension.
No takes yet. Share an insight, caveat, or question.
Ding et al. (2022) conducted an observational in Essential hypertension (n=100). Essential hypertension vs. Healthy adults was evaluated on Prediction of hypertension using pressure-strain loop parameters. Noninvasive pressure-strain loop parameters effectively predicted hypertension, with global work index showing 97.5% specificity and global constructive work showing 95% sensitivity.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: