Synthesis of C‐Disaccharides through a One‐Pot Alkynol Cycloisomerization‐Reductive Deoxygenation

This is the authors' abstract. We don't add key points for this paper.

A sweet disposition: Simple protocols for the synthesis of (1→1)- and (1→6)-linked C-disaccharides have been developed (see scheme). A one-pot Au-catalyzed alkynol cycloisomerization followed by BF3⋅Et2O, Et3SiH reduction has been established as the key reaction for C-disaccharide synthesis including all possible pyran–pyran, furan–furan, and pyran–furan combinations.