Key result
AVR with posterior root enlargement shows ~10% early mortality alongside improved peak gradients and LVEF.
Why the study?
Posterior root enlargement allows implantation of suitable-sized prosthetic valves in patients with a small aortic root, but long-term results were not well evaluated.
Cohort (n=103)
Aortic valve replacement with posterior root enlargement is a safe and effective technique for patients with a small aortic annulus, significantly improving hemodynamics and left ventricular ejection fraction.
Supports consideration in small aortic annuli; extends observational data but leaves open randomized confirmation.
BACKGROUND: Posterior root enlargement provides the implantation of suitable-sized prosthetic valves in patients with a small aortic root. The aim of this study was to evaluate the long-term results of posterior root enlargement in patients undergoing aortic valve replacement. METHODS: Between 1997 and 2011, 103 patients with a small aortic annulus (indexed effective orifice area < 0.75 cm(-2) · m(-2)) underwent aortic valve replacement with posterior aortic root enlargement. Forty-six (44%) patients were male. The mean age was 28.62 ± 18.56 years. Survivors were followed up for a mean of 45.6 ± 32.4 months. RESULTS: Early mortality was 9.6%. The most common cause of early mortality was low cardiac output syndrome (6 patients). There were 2 (1.9%) late deaths due to cerebrovascular events. During the follow-up period, mild paravalvular leakage occurred in only one (1%) patient, and one suffered a malfunction of the prosthesis. A significant reduction was seen in the peak pressure gradients across the replaced aortic valves (p < 0.001). Moreover, a significant increase was noted in left ventricular ejection fraction (p = 0.001). CONCLUSIONS: Aortic root enlargement using the Manouguian technique can be applied with acceptable safety. It effectively decreases postoperative gradients and increases left ventricular ejection fraction. Short- and long-term mortality and morbidity rates are satisfactory.
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Ghavidel et al. (2014) conducted a cohort in Small aortic annulus (n=103). Aortic valve replacement with posterior root enlargement was evaluated on Early mortality. Aortic valve replacement with posterior root enlargement resulted in 9.6% early mortality, significantly improved peak pressure gradients (P<0.001), and increased LVEF (P=0.001).
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