Key result
Surgical resection with ECMO yields 2-year symptom-free survival for rare pulmonary artery myxofibrosarcoma in pregnancy.
Why the study?
Pulmonary artery myxofibrosarcoma presenting as diffuse pulmonary embolism in pregnancy is a rare clinical entity requiring detailed case description.
Case Report (n=1)
No
Highlights a rare presentation of primary pulmonary artery myxofibrosarcoma mimicking pulmonary embolism during pregnancy.
May guide rare tumor management in pregnancy; leaves open generalizability and optimal protocols pending further cases.
A 37-year-old female patient presented with shortness of breath, cough, and chest pain complaints from the 12th week of her first pregnancy. At the 28th week, labor induction had to be performed because of severe dyspnea and hyoxemia. Thereafter, a diffused pulmonary embolism was detected by echocardiography and CT angiography, without histological diagnosis. Pulmonary endarterectomy was performed, and it was found during operation that a huge, lobular mass originated in the posterior wall and extended throughout the vasculature of both lungs, and a mucinous pellicle covered the entire pulmonary endothelium. Pathology revealed a low-grade myxofibrosarcoma with positive vimentin and SMA, partially positive CD-34.
No takes yet. Share an insight, caveat, or question.
Xiang et al. (2022) conducted a case report in Primary diffused pulmonary artery myxofibrosarcoma (n=1). Pulmonary endarterectomy with ECMO support was evaluated on Clinical recovery. Surgical resection with ECMO support successfully treated a rare primary diffused pulmonary artery myxofibrosarcoma in a pregnant patient, with no obvious respiratory symptoms at 2 years.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: