Key result
Chronic thigh wound and dyspnea reveal metastatic cutaneous angiosarcoma causing rapidly fatal multiorgan failure.
Why the study?
Metastatic cutaneous angiosarcoma is a rare entity with limited clinical descriptions and diagnostic challenges.
Case Report (n=1)
This case report highlights a rare presentation of metastatic cutaneous angiosarcoma with pulmonary and lymph node involvement.
Raises suspicion for angiosarcoma in nonhealing wounds with dyspnea; leaves open optimal diagnostic approaches for this rare entity.
We present a case of a 56-year-old female presented with a chief complaint of four months of dyspnea that had acutely worsened. The patient also reported a chronic right thigh wound. Chest radiograph on initial presentation demonstrated multiple bilateral rounded opacities. CT pulmonary angiogram demonstrated multiple bilateral rounded nodules seen on chest radiograph along with a right upper lobe pulmonary artery with near-complete compression secondary to large right hilar adenopathy. CT of right lower extremity showed evidence of ulceration with multiple conglomerate subcutaneous masses, predominately anteriorly and laterally. She underwent a bronchoscopy; a fine-needle aspiration of the subcarinal lymph node was taken. A surgical biopsy from the right thigh wound was also performed. A histological examination from the right thigh ulcer and subcarinal lymph node demonstrated high-grade spindle cell neoplasm, positive for CD-31 and consistent with angiosarcoma.
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JIMENEZ et al. (2021) conducted a case report in Metastatic Cutaneous Angiosarcoma (n=1). A 56-year-old female presenting with a chronic thigh wound and worsening dyspnea was diagnosed with cutaneous angiosarcoma metastatic to the lungs and rapidly expired due to multiorgan failure.
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