Key result
Evaluation finds DVT prophylaxis dosing with heparin or enoxaparin appropriate in ~77% of patients.
Why the study?
Accurate anticoagulant use is critical due to complications from DVT and PE, but adherence to guidelines in clinical practice is uncertain.
Cross-Sectional (n=400)
No
Despite comprehensive guidelines, anticoagulant utilization for DVT/PE prevention and treatment is not performed accurately in the hospital setting.
BACKGROUND AND GOAL: Due to the importance of anticoagulation use along with the complications that deep vein thrombosis (DVT) and pulmonary embolism (PE) may bring about for the patients, in this study we decided to carry out a drug utilization evaluation on anticoagulants that are routinely administered in a tertiary teaching hospital. METHOD: Anticoagulants utilization was evaluated in 400 patients from 4 wards (infectious disease, cardiology, nephrology, and cardiac care unit) of a tertiary teaching hospital in a cross-sectional, prospective study. RESULTS: According to the risk stratification, 220 (55%) of the evaluated patients have indication to receive anticoagulants as deep venous thrombosis prophylaxis. With definite diagnosis of DVT or PE, 169 (42.3%) patients have received anticoagulant therapy. In 11 (2.8%) cases, anticoagulants has been ordered inappropriately. In assessment of the anticoagulants regimens that were used as DVT prophylaxis doses of heparin and enoxaparin were appropriate in 75% and 79% of patients, respectively. CONCLUSION: Despite the existence of comprehensive guidelines for the prevention and treatment of DVT and PE, it is not performed accurately.
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Khalili et al. (2010) conducted a cross-sectional in Deep vein thrombosis and pulmonary embolism prophylaxis or treatment (n=400). Anticoagulant therapy was evaluated on Appropriateness of anticoagulant utilization. Anticoagulant utilization evaluation revealed that DVT prophylaxis dosing was appropriate in 75% of patients receiving heparin and 79% receiving enoxaparin.
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