Key result
Incident metabolic syndrome in elderly women is linked to ~94% faster carotid IMT progression.
Why the study?
Data on the association of metabolic syndrome with progression of subclinical atherosclerosis in elderly women are limited.
Does incident metabolic syndrome accelerate the progression of carotid IMT in elderly women?
Population
101 elderly women aged 60-70 years from a population-based sample
Comparison
Incident metabolic syndrome vs no development of metabolic syndrome during 12 years
Design
12-year population-based cohort study
Follow-up
12 years
Authors
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May identify higher-risk elderly women for carotid atherosclerosis progression; hypothesis-generating and does not yet support practice change.
Cohort (n=101)
Does incident metabolic syndrome accelerate the progression of carotid IMT in elderly women?
Absolute Event Rate: 0.31% vs 0.16%
p-value: p=.04
Incident metabolic syndrome is associated with accelerated progression of subclinical atherosclerosis, as measured by carotid IMT, in elderly women.
Hassinen et al. (2006) conducted a cohort in Metabolic syndrome and subclinical atherosclerosis (n=101). Incident metabolic syndrome vs. No incident metabolic syndrome was evaluated on Increase in carotid intima-media thickness (IMT) (p=.04). Incident metabolic syndrome in elderly women was associated with accelerated progression of carotid intima-media thickness over 12 years compared to those without it (0.31 mm vs 0.16 mm; P=0.04).
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