Key result
Activating Ca++-activated K+ channels during ischemia may protect lung grafts and improve transplant outcomes.
Should not yet alter lung transplant protocols; leaves open whether Ca++-activated K+ channel activation protects grafts.
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Mohamed S. A. Mohamed (2015) conducted a letter in Ischemia-reperfusion injury in lung transplantation. Activation of Ca++-activated K+ channels was evaluated. Pharmacological activation of Ca++-activated K+ channels during lung graft ischemia is proposed as a potential target to protect the lung graft and improve clinical outcomes in transplantation.
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