What question did this study set out to answer?

To synthesize existing evidence on the antibacterial and antifungal activities of nine traditionally used medicinal plants against drug-resistant microbial pathogens.

July 9, 2026Frontiers in PharmacologyOpen Access

Antimicrobial potential of selected medicinal plants against drug-resistant pathogens: a systematic review

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Authors

SAShuroug A. Alowais RARuya Alshkrh AAAhmad Abdulaziz Al-Owais

Discussion

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Overview

Systematic review reveals broad-spectrum antimicrobial activity across nine traditional medicinal plants, suggesting viable alternatives against drug-resistant pathogens.

Key Points

To synthesize existing evidence on the antibacterial and antifungal activities of nine traditionally used medicinal plants against drug-resistant microbial pathogens.
Conducted a systematic review following PRISMA guidelines via Google Scholar for in vitro and in vivo studies published between January 1, 2000, and August 1, 2025.
Identified 56 eligible English-language studies evaluating extract and metabolite efficacy, extracting metrics including minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and inhibition zones.
Lepidium sativum, Saussurea costus, Rhus tripartita, and Chenopodium murale demonstrated broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria, alongside marked antifungal actions against Candida species.
Advanced processing via supercritical fluid extraction and green synthesis of silver nanoparticles significantly enhanced bioactivity, consistently yielding lower MIC values and larger inhibition zones compared to conventional solvent extracts.

Cite This Study

Alowais et al. (2026) studied this question.

synapsesocial.com/papers/6aaf3462a7e31fa2e934fb1f https://doi.org/10.3389/fphar.2026.1735625

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July 9, 2026Frontiers in PharmacologyOpen Access

Antimicrobial potential of selected medicinal plants against drug-resistant pathogens: a systematic review

View Full Paper

Ask AI

Bookmark

Authors

SAShuroug A. Alowais RARuya Alshkrh AAAhmad Abdulaziz Al-Owais

Discussion

Member takes

Overview

Systematic review reveals broad-spectrum antimicrobial activity across nine traditional medicinal plants, suggesting viable alternatives against drug-resistant pathogens.

Key Points

To synthesize existing evidence on the antibacterial and antifungal activities of nine traditionally used medicinal plants against drug-resistant microbial pathogens.
Conducted a systematic review following PRISMA guidelines via Google Scholar for in vitro and in vivo studies published between January 1, 2000, and August 1, 2025.
Identified 56 eligible English-language studies evaluating extract and metabolite efficacy, extracting metrics including minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and inhibition zones.
Lepidium sativum, Saussurea costus, Rhus tripartita, and Chenopodium murale demonstrated broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria, alongside marked antifungal actions against Candida species.
Advanced processing via supercritical fluid extraction and green synthesis of silver nanoparticles significantly enhanced bioactivity, consistently yielding lower MIC values and larger inhibition zones compared to conventional solvent extracts.

Cite This Study

Alowais et al. (2026) studied this question.

synapsesocial.com/papers/6aaf3462a7e31fa2e934fb1f https://doi.org/10.3389/fphar.2026.1735625

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