Key result
High-flow AVFs are linked to cardiovascular complications including high-output heart failure, LVH, and pulmonary hypertension.
Why the study?
Arteriovenous access creation in hemodialysis patients is implicated in adverse cardiac outcomes and deterioration of pre-existing cardiovascular disease, with unclear clinical impact and management strategies.
Population
Hemodialysis patients with arteriovenous access
Comparison
Arteriovenous fistulas versus grafts and flow-restrictive procedures for high-flow AVFs
Design
Narrative review from a multidisciplinary team perspective
Authors
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May warrant pre-access cardiac evaluation in hemodialysis; leaves open randomized comparison of fistula versus graft effects.
High-flow arteriovenous fistulas can lead to significant cardiac complications such as high-output heart failure, necessitating careful pre-procedural cardiac evaluation and potential flow-restrictive interventions in symptomatic patients.
Stathopoulou et al. (2025) conducted a review in End-stage kidney disease with arteriovenous access. Arteriovenous fistula was evaluated. Arteriovenous fistulas can cause or exacerbate cardiovascular complications such as high-output heart failure, left ventricular hypertrophy, and pulmonary hypertension, necessitating close monitoring of high-flow access.
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