Key result
3D TTE-guided transcatheter closure successfully treats multiple post-infarct ventricular septal ruptures.
Why the study?
Post-infarct ventricular septal rupture is a rare but serious complication of acute myocardial infarction with challenges in management using transcatheter closure.
Case Report (n=1)
3D transthoracic echocardiography is a valuable imaging modality for accurately delineating complex, multiple post-infarct ventricular septal ruptures and guiding successful percutaneous transcatheter closure.
May support 3D TTE-guided closure in select complex post-MI VSR; hypothesis-generating and requires prospective validation before practice change.
BACKGROUND: Post-infarct ventricular septal rupture (PI-VSR) is a rare complication of acute myocardial infarction (AMI) but has very serious implications. Managing PI-VSR using transcatheter closure (TCC) presents varying challenges depending on the patient's condition. The aim of this study is to present a highly challenging case of multiple VSRs as a complication of AMI. CASE PRESENTATION: A 59-year-old male was admitted with symptoms of shortness of breath, dyspnea on exertion, orthopnea, and swelling of the lower extremities. He had typical chest pain related to infarction 2 weeks before his admission. On electrocardiogram (ECG) examination, evidence of an old myocardial infarction in the infero-antero-lateral regions was seen. Echocardiography showed mild mitral and tricuspid regularities. The left ventricular (LV) systolic function was mildly compromised, with a global ejection fraction of 44%. There was also a left-to-right VSR shunt in the apical region of the LV. Multiple defects as outlined by 3D transthoracic echocardiography (TTE)-the largest measuring 17 mm. Given the high risks of open-heart surgery, a percutaneous closure of the VSR was carried out using a 21 mm atrial septal defect (ASD) occluder. The device was satisfactorily placed, and there was an improvement in the clinical condition of the patient. He was discharged after his 8-day stay in the hospital. CONCLUSION: Our study emphasizes that echocardiography with 3D imaging provides a more detailed view of the size and shape of the rupture and serves as a valuable modality for guiding the percutaneous transcatheter VSR closure procedure.
No takes yet. Share an insight, caveat, or question.
Ardini et al. (2025) conducted a case report in Post-infarct ventricular septal rupture (PI-VSR) after acute myocardial infarction (n=1). Transcatheter closure guided by 3D transthoracic echocardiography was evaluated on Successful device placement and clinical improvement. Transcatheter closure guided by 3D transthoracic echocardiography successfully treated multiple post-infarct ventricular septal ruptures, leading to clinical improvement and hospital discharge.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: