Key result
Reciprocal ventricular extrasystoles arise from re-entry via functional A-V node dissociation into two unidirectional pathways.
Why the study?
The mechanism of reciprocal or return ventricular extrasystoles involving re-entry through the A-V node pathways requires detailed explanation.
Describes the electrophysiological mechanism of reciprocal ventricular extrasystoles based on longitudinal dissociation of the A-V node.
May guide arrhythmia mechanism interpretation; leaves open prospective validation in contemporary EP cohorts.
An impulse originating in the A-V node or ventricles may be conducted retrogradely through the A-V node.The retrograde impulse may, under certain circumstances, return anterogradely through the A-V node to the ventricles giving rise to a reciprocal or return extrasystole.One explana- tion for this re-entry phenomenon is based on the concept of a functional vertical division or longi- tudinal dissociation of the A-V node into two pathways (Schmitt and Erlanger, 1928)-(A) a non- refractory pathway that conducts retrograde impulses from the lower centre, and (B) a refractory pathway that blocks retrograde impulses from the lower centre but can conduct impulses anterogradely, i.e. it has the property of unidirectional conduction.The impulse from the lower centre is thus conducted retrogradely through the non-refractory pathway, A, and after reaching the upper regions of the node is conducted anterogradely through the second pathway, B. To enable the retrograde impulse to re-enter the second pathway, deep retro- grade penetration of the A-V node to a critical level is necessary.The level at which re-entry can occur will be referred to as the re-entry level.In the case of A-V nodal rhythm this mechanism will result in an inverted "nodal" P wave " sandwiched " between two normal QRS complexes (L in Fig. 1).Should this mechanism occur with1.-Diagrammatic illustration of various mechanisms in reciprocal rhythm.A=atrial level; A-V=atrio-nodal level; V=ventricular level; the dotted line r.l.represents the re-entry level.Full explanation in text.
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Schamroth et al. (1962) conducted a review in Reciprocal ventricular extrasystoles. Reciprocal ventricular extrasystoles can be explained by a re-entry phenomenon based on the functional longitudinal dissociation of the A-V node into two pathways with unidirectional conduction.
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