Key result
RV 2D global strain uniquely correlates with CMR RVEF among non-volumetric echo markers in Ebstein's anomaly.
Why the study?
Data on echocardiographic quantification of right ventricular function in Ebstein’s anomaly are rare, necessitating evaluation of non-volumetric indices against CMR-derived ejection fraction.
Do non-volumetric echocardiographic indices of RV function correlate with CMR-derived RV ejection fraction in patients with Ebstein's anomaly?
Cross-Sectional (n=49)
Do non-volumetric echocardiographic indices of RV function correlate with CMR-derived RV ejection fraction in patients with Ebstein's anomaly?
In patients with Ebstein's anomaly, RV 2D global strain is the only non-volumetric echocardiographic parameter that significantly correlates with CMR-derived RV ejection fraction, whereas TAPSE and myocardial velocities correlate poorly.
Background: Ebstein’s anomaly is often associated with RV dysfunction. Data on echocardiographic quantification of RV function in this anomaly are however rare. The aim of this study was to determine which non-volumetric echocardiographic index of global systolic RV function correlates well with CMR-derived RV ejection fraction. Methods and Results: We therefore compared 8 non-volumetric echocardiographic indices of RV function with the gold standard cardiovascular magnetic resonance (CMR). 49 patients with an Ebstein anomaly and a mean age of 32 ± 18 years were examined. Tricuspid annular plane systolic excursion (TAPSE), tissue Doppler myocardial velocities (peak S, IVA, strain peak S and strain rate peak S) as well as 2D strain measures (2D strain longitudinal peak S, 2D strain rate longitudinal peak S and 2D global strain) for the RV were compared with CMR-derived ejection fraction values. Of the 8 echocardiographic parameters investigated, only 2D global strain showed a significant correlation with CMR-derived RVEF (R= −0.4, p = 0.01). Conclusion: The only non-volumetric echocardiographic parameter which correlates with CMR derived RV ejection fraction in patients with the Ebstein anomaly was RV 2D global strain. TAPSE and myocardial velocities correlated poorly and should not be used.
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Kuhn et al. (2015) conducted a cross-sectional in Ebstein's anomaly (n=49). Non-volumetric echocardiographic indices vs. Cardiovascular magnetic resonance (CMR) was evaluated on Correlation with CMR-derived RV ejection fraction (R= -0.4, p=0.01). RV 2D global strain was the only non-volumetric echocardiographic parameter that significantly correlated with CMR-derived RV ejection fraction in Ebstein's anomaly (R= -0.4, p=0.01).
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