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BackgroundFOLFOX (folinic acid, 5-fluorouracil, and oxaliplatin) is an adjuvant chemotherapy used for colon cancer.5-Fluorouracil (5-FU), a component of FOLFOX, is one of the most common chemotherapy drugs used for cancer treatment.Common side effects of the FOLFOX therapy include increased risk of infection, shortness of breath, bruising, bleeding, fatigue, diarrhea, neuropathy, and mouth sores.More rare side effects, however, do include heart problems that can cause chest pain, arrhythmias, myocardial infarction, or heart failure due to coronary vasospasm caused by 5-fluorouracil. Case PresentationOur case shows a 68-year-old Caucasian male actively being treated with FOLFOX therapy for colon cancer and developing a severe myocardial infarction with cardiogenic shock from chemotherapy.We demonstrate a unique presentation of therapy manipulation to allow patients to receive chemotherapy while reducing the risk of recurrent myocardial infarction. Conclusion:With this therapy modification, our patient could continue with further treatment cycles of FOLFOX therapy for his cancer treatment.
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