Key result
High-altitude egg incubation is linked to less RV hypertrophy, driven by increased cardiopulmonary parameters.
Why the study?
The involvement of anatomical parameters of the cardiopulmonary system in the development of ascites syndrome in broiler chickens under different altitude conditions was not fully understood.
Population
Day-old broiler chickens hatched from eggs of a broiler line
Comparison
Incubation at high altitude vs incubation at low altitude
Design
Preclinical study
Follow-up
Day-old
Authors
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Embryonic high-altitude hypoxia may program lower ascites risk in broilers; hypothesis-generating for developmental cardioprotection in pulmonary hypertension.
Chronic hypoxia during embryonic development at high altitude alters cardiopulmonary developmental trajectories in broiler chickens, lowering susceptibility to pulmonary hypertension and ascites.
Hassanzadeh et al. (2008) studied Ascites syndrome and right ventricular hypertrophy. Incubation at high altitude vs. Incubation at low altitude was evaluated on Relative heart and lung weights, volumes, and incidence of right ventricular hypertrophy and ascites. Incubation of broiler chicken eggs at high altitude increased relative cardiopulmonary parameters and was associated with a lower incidence of right ventricular hypertrophy and ascites.
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