Key result
Acoustic cardiography S3 strength accurately diagnoses early LV systolic dysfunction after MI with ~0.94 AUC.
Why the study?
The clinical value of acoustic cardiography in diagnosing coronary artery disease and early asymptomatic left ventricular systolic dysfunction after PCI was unclear.
Does acoustic cardiography accurately diagnose CAD and early asymptomatic left ventricular systolic dysfunction post-PCI in cardiology inpatients?
Observational (n=315)
Does acoustic cardiography accurately diagnose CAD and early asymptomatic left ventricular systolic dysfunction post-PCI in cardiology inpatients?
Acoustic cardiography, particularly S3 strength, provides a non-invasive and effective method for diagnosing early asymptomatic left ventricular systolic dysfunction after myocardial infarction.
Acoustic cardiography may aid CAD diagnosis and post-PCI LV dysfunction detection; leaves open need for prospective validation before practice change.
BACKGROUND: To investigate the clinical value of acoustic cardiography in the diagnosis of coronary artery disease (CAD) and post-percutaneous coronary intervention (PCI) early asymptomatic left ventricular systolic dysfunction. METHODS: Inpatients in the department of cardiology were included in the research (n = 315); including 180 patients with angina pectoris and 135 patients with acute anterior wall myocardial infarction after emergency PCI did not present with signs and symptoms of heart failure. Color Doppler echocardiography, brain natriuretic peptide, acoustic cardiography examination were performed. The patients were divided into four groups: non-CAD group (n = 60), CAD group (n = 120), MIREF group (EF% < 50%, n = 75), and MINEF group (EF% ≥ 50%, n = 60). RESULTS: Acoustic cardiography parameters EMATc, systolic dysfunction index, S3 strength and S4 strength in the MIREF group were higher than those in MINEF group (p < .05), and the MINEF group was higher than CAD group (p < .05). S3 strength (area under the curve [AUC] 0.67, 95% CI 0.585-0.755, p < .001) and S4 strength (AUC 0.617, 95% CI 0.536-0.698, p = .011) are useful in the diagnosis of CAD. S3 strength (AUC 0.942, 95% CI 0.807-0.978, p < .001) was superior to other indicators in the diagnosis of early left ventricular systolic dysfunction after myocardial infarction. CONCLUSION: S4 combined with STT standard change can improve the diagnosis of CAD. Acoustic cardiography can be used as a non-invasive, rapid, effective, and simple method for the diagnosis of asymptomatic left ventricular systolic dysfunction in the early stage after myocardial infarction.
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Zhang et al. (2021) conducted an observational in Coronary artery disease and post-PCI early asymptomatic left ventricular systolic dysfunction (n=315). Acoustic cardiography was evaluated on Diagnosis of early left ventricular systolic dysfunction after myocardial infarction using S3 strength (AUC 0.942, 95% CI 0.807-0.978, p=<.001). Acoustic cardiography S3 strength accurately diagnosed early left ventricular systolic dysfunction after myocardial infarction (AUC 0.942; 95% CI 0.807-0.978; p<0.001).
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