Key result
Acoustic cardiography detects S3 in ~30% of patients with LVEF <50%, correlating with impaired LV function.
Why the study?
Simultaneous electrocardiographic and heart sound data have been shown to be helpful for detecting LV systolic dysfunction in the outpatient setting, but correlation with echocardiography parameters needed evaluation.
Does acoustic cardiography correlate with Doppler echocardiography for the detection of left ventricular systolic dysfunction in patients with suspected or known cardiac disease?
Cross-Sectional (n=161)
Does acoustic cardiography correlate with Doppler echocardiography for the detection of left ventricular systolic dysfunction in patients with suspected or known cardiac disease?
Absolute Event Rate: 30.4% vs 9.8%
Acoustic cardiography provides an accessible and reliable outpatient method to detect S3 and assess left ventricular systolic dysfunction, correlating well with echocardiographic findings.
Acoustic cardiography may aid outpatient LV dysfunction detection; leaves open whether it improves outcomes versus echocardiography alone.
For detection of left ventricular (LV) systolic dysfunction in the outpatient setting, simultaneous electrocardiographic and heart sound data have been shown to be helpful. In 161 patients with suspected or known cardiac disease, echocardiography and acoustic cardiography were performed. Acoustic cardiographic parameters correlated to echocardiography included: presence or absence of S3, electromechanical activation time (EMAT), LV systolic time (LVST), and EMAT/LVST. LV ejection fraction was >or=50% in 82 patients (S3 present in 9.8%) and <50% in 79 patients (S3 present in 30.4%; the <50% group also had a greater EMAT, EMAT/LVST, and lower mean LVST [p<0.05]). Patients with an S3 had a lower ejection fraction, larger mean left atrial and LV dimensions, and an increased proportion of diastolic dysfunction. Acoustic cardiography allows reliable detection of the S3, which correlates with echocardiographic evidence of impaired LV function, and the EMAT/LVST ratio reflects reduced ejection fraction, providing an affordable, accessible means to assess LV dysfunction in the outpatient setting.
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Züber et al. (2006) conducted a cross-sectional in suspected or known cardiac disease (n=161). Acoustic cardiography vs. Echocardiography was evaluated on Presence of S3 in patients with LVEF <50% vs ≥50%. Acoustic cardiography detected an S3 in 30.4% of patients with LVEF <50% compared to 9.8% in those with LVEF ≥50%, correlating with echocardiographic evidence of impaired LV function.
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