Key result
Beta-blockers lack adequate randomized trials assessing exercise conditioning in coronary patients without exercise-induced ischemia.
Why the study?
The effects of beta-adrenergic blockers on exercise conditioning in coronary patients without exercise-induced ischemia have not been adequately studied, and prior studies lack randomization to beta-blocker versus placebo.
Do beta-adrenergic blocking agents limit exercise conditioning in coronary patients without exercise-induced ischemia?
Population
Heterogeneous groups of coronary patients including those with exertional angina and without exercise-induced ischemia
Comparison
Beta-adrenergic receptor blocking agents versus placebo
Design
Review of available studies lacking randomization
Authors
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Exercise conditioning may occur on beta-blockers in coronary patients; leaves open whether randomization would modify observed responses.
Do beta-adrenergic blocking agents limit exercise conditioning in coronary patients without exercise-induced ischemia?
This review highlights the lack of randomized data on whether beta-blockers attenuate exercise conditioning in coronary patients without exercise-induced ischemia.
Blood et al. (1988) conducted a review in Coronary artery disease. Beta-adrenergic receptor blocking agents vs. Placebo was evaluated on Exercise conditioning. Beta-adrenergic blockade effects on exercise conditioning in coronary patients without exercise-induced ischemia remain inadequately studied due to a lack of randomized, placebo-controlled trials.
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