Key result
Maintaining SBP <150 mmHg during carotid cross-clamping is linked to 0% stroke or mortality.
Why the study?
Monitoring cerebral perfusion during carotid endarterectomy is important to prevent ischemia, and the effect of maintaining arterial blood pressure below 150mmHg during cross-clamping on cerebral saturation was evaluated.
Does maintaining systolic arterial blood pressure below 150mmHg during cross-clamping affect cerebral saturation in patients undergoing carotid endarterectomy?
Observational (n=60)
No
Does maintaining systolic arterial blood pressure below 150mmHg during cross-clamping affect cerebral saturation in patients undergoing carotid endarterectomy?
Maintaining systolic arterial blood pressure below 150mmHg during cross-clamping in carotid endarterectomy appears safe based on NIRS findings and clinical observations.
Aim: Monitoring of cerebral perfusion during carotid endarterectomy helps to institute early intervention to prevent risk of ischemia during the operation. We aimed to evaluate if the disadvantages of high systemic pressure can be avoided by keeping arterial blood pressure below 150mmHg during cross-clamping of the internal carotid artery by correlating our findings of NIRS values with clinical results Material and Method: This was designed as a prospective study that included elective patients scheduled for an operation of carotid artery stenosis under general anesthesia. A total of 60 patients operated on between August and October 2019 were included in the study. Results: Patients' NIRS findings on the right and left hemispheres were analyzed separately to be able to differentiate any possible changes of NIRS of the cerebral hemisphere ipsilateral to the clamped carotid artery. The analysis of the right and left NIRS findings in these 60 patients revealed a significant decrease between intubation and incision NIRS values (p=0.008 and p= 0.02respectively). Conclusion: Considering the NIRS findings and clinical observations of the patients in the postoperative period, we think that ICA endarterectomy operations may be safe to perform in a suitable patient group while the systolic arterial blood pressure is maintained below 150mmHg during cross-clamping.
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Yücel et al. (2021) conducted an observational in Carotid artery stenosis (n=60). Maintenance of systolic arterial blood pressure below 150 mmHg was evaluated on Change in cerebral oxygen saturation (NIRS) during internal carotid artery cross-clamping. Maintaining systolic blood pressure below 150 mmHg during carotid cross-clamping resulted in no significant decrease in cerebral oxygen saturation and a 0% rate of permanent stroke or mortality.
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