Key result
Bupivacaine infiltration reduces 6-hour post-tonsillectomy pain scores by ~38% versus no infiltration.
Why the study?
Post tonsillectomy pain affects 30-70% of patients and impacts analgesic use, hospital stay, and return to normal activity, necessitating effective pain management strategies.
Does bupivacaine infiltration reduce postoperative pain in patients undergoing tonsillectomy?
RCT (n=32)
Prospective randomized controlled
No
Does bupivacaine infiltration reduce postoperative pain in patients undergoing tonsillectomy?
Absolute Event Rate: 2.19% vs 3.56%
p-value: p=0.001
Infiltration of 0.25% bupivacaine significantly reduces post-tonsillectomy pain.
Supports bupivacaine infiltration to reduce 6-hour post-tonsillectomy pain; confirms local anesthetic efficacy in tonsillectomy.
Background: Tonsillectomy is a common surgical procedure required to prevent recurrent infection, inflammation and related distress to the patients. Intervention in this highly vascularized area results in inflammatory responses and subsequent pain. Due to inadequate management 30-70% patients suffer from post-operative pain. Post tonsillectomy pain has its impact on analgesic consumption, hospital stay and return to normal activity. Methodology: This randomized control trial study design is a prospective randomized controlled including convenience sample of 32 patients of both genders, aged 4-30 years undergoing tonsillectomy.Tonsillectomy was performed by standard dissection method after giving general anesthesia to the patients. After completing the tonsillectomy on right side, surgeon infiltrated 6ml of 0.25 % bupivacaine in the tonsillar fossa on the right side. The surgeon did not infiltrate into the left side being observed as control. Postoperative pain score was recorded by asking patients on a VAS graded 1-10 scale (0= no pain and 10= maximum pain) after half an hour in recovery, 2 hours, 4 hours and 6 hours after the operation. Results: The mean age of the study patients was 14.08±7.32 years which included 20 (62.5%) females and 12(37.5%) males. The mean of duration of operation was 42.03±14.75 minutes. There was statistically significant difference between pain scores on VAS in infiltrated bupivacaine (right side) and control (left side) after ½, 2,4 and 6 hours respectively. Conclusion: Infiltration of 0.25% bupivacaine significantly reduces post tonsillectomy pain.
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Kousar et al. (2021) conducted an RCT in Post-tonsillectomy pain (n=32). Bupivacaine infiltration vs. No infiltration (contralateral side) was evaluated on Visual Analogue Scale (VAS) pain score at 6 hours postoperatively (p=0.001). Infiltration of 0.25% bupivacaine significantly reduced post-tonsillectomy pain scores at 6 hours compared to no infiltration on the contralateral side (VAS 2.19 vs 3.56, p=0.001).
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