Key result
CO-RADS score demonstrates comparable COVID-19 diagnostic sensitivity to lymphopenia and NLR.
Why the study?
The correlation between CO-RADS score and CBC indices and the comparative sensitivity of CO-RADS versus lymphopenia and neutrophil/lymphocyte ratio in diagnosing COVID-19 were not established.
Does CO-RADS score have higher sensitivity compared to lymphopenia and neutrophil/lymphocyte ratio in diagnosing COVID-19 in symptomatic emergency room patients?
Observational (n=106)
No
Does CO-RADS score have higher sensitivity compared to lymphopenia and neutrophil/lymphocyte ratio in diagnosing COVID-19 in symptomatic emergency room patients?
CO-RADS score and lymphopenia are rapid and valuable tools in the diagnosis of COVID-19, with CO-RADS showing 60-71% sensitivity and lymphopenia showing 40-82% sensitivity.
No correlation between CORADS and CBC indices in this retrospective cohort; leaves open whether imaging or hematologic markers best complement PCR for COVID-19 diagnosis.
The global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) generated a pandemic which severely impacted on care delivery worldwide. Aim of the work: To assess the correlation between CORADS score and different CBC indices and the sensitivity of CORADs score compared to lympopenia and neutrophil/ lymphocyte ratio in diagnosing patients with COVID- 19. Patients and methods :This study is a retrospective data review study done 106 patients who were visiting the emergency room at Benha University hospital for assessment of symptoms for the possibility of COVID 19.Results: Symptoms were variable ; the most common was fever (92.5%), mean total leucocytic count (TLC) 7.5±3.4 (10*3/UL); neutrophil count 5.5±3.3 (10*3/UL), lymphocytic count was 1.42 ± 0.77.CT scan done to all patients where GGO was the most common pattern. CORAD score was ranging from 0 to 5 with mean 3.96±1.59, There was no correlation between CORAD score and different CBC parameters; CORAD scores ≥ 4 had a sensitivity of 71% while CORAD 5 has a sensitivity of 60% in diagnosis. Lymphopenia 2.4. Conclusion: CORAD score and lymphopenia are rapid and valuable tools in diagnosis of COVID 19. CORAD has a sensitivity 60 to 71% according to the cut off used while lymphopenia has a sensitivity 40 to 82%, neutrophil/ lymphocyte ratio 61 to 68%.
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Allam et al. (2022) conducted an observational in COVID-19 (n=106). CO-RADS score vs. Lymphopenia and neutrophil/lymphocyte ratio was evaluated on Sensitivity in diagnosing COVID-19. CO-RADS score demonstrated a sensitivity of 60% to 71% for diagnosing COVID-19, compared to 40% to 82% for lymphopenia and 61% to 68% for neutrophil/lymphocyte ratio.
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