Key result
Definitive evidence for a pathogenetic role of IFN-gamma in clinical cardiac transplantation graft arteriosclerosis is lacking, despite compelling evidence from murine models.
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While preclinical models strongly implicate IFN-gamma in the pathogenesis of cardiac graft arteriosclerosis, its exact role in clinical human heart transplantation remains to be definitively proven.
While preclinical models strongly implicate IFN-gamma in the pathogenesis of cardiac graft arteriosclerosis, its exact role in clinical human heart transplantation remains to be definitively proven.
George Tellides (2006) conducted a review in Cardiac Graft Arteriosclerosis. IFN-gamma was evaluated. Definitive evidence for a pathogenetic role of IFN-gamma in clinical cardiac transplantation graft arteriosclerosis is lacking, despite compelling evidence from murine models.
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