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Article1 June 1930Hourly Rhythms in Blood Pressure in Persons With Normal and Elevated PressuresSELMA C. MUELLER, M.D., GEORGE E. BROWN, M.D.SELMA C. MUELLER, M.D., GEORGE E. BROWN, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-3-12-1190 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt has been known that the systemic blood pressure is not fixed, but is subject to variations from moment to moment and from hour to hour. Many workers have called attention to this variability of the blood pressure, particularly in certain forms of essential hypertension. It, however, has not been demonstrated whether there is any constant rhythm or variation in vasomotor activity in the curve of twenty-four hours. Studies have been carried out, notably by Campbell and Blankenhorn, in which, during sleep, there has been demonstrated a gradual fall in vasomotor activity succeeded by a rise in the early morning...Bibliography1 BROOKSCARROLL HJH: A clinical study of the effects of sleep and rest on blood-pressure. Arch. Int. Med., 10: 97-102 (May) 1912. CrossrefGoogle Scholar2 BRUSHFAYERWEATHER CER: Observations on the changes in blood-pressure during normal sleep. Am. Jour. Physiol., 5: 199-210 (April) 1901. CrossrefGoogle Scholar3 CAMPBELLBLANKENHORN HEMA: Effect of sleep on normal and high blood pressure. Am. Heart Jour., 1: 151-159 (Dec.) 1925. CrossrefGoogle Scholar4 COLOMBO C: Recherches sur la pression du sang chez l'homme. Arch. ital. d. biol., 31: 345-369, 1899. 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CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Division of Medicine The Mayo Clinic Rochester, Minnesota*Submitted for publication February 17, 1930. 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