Key result
Regional use of fractional flow reserve was significantly and inversely related to the number of PCIs performed per million inhabitants for stable ischemic heart disease in Italy (P=0.01).
Why the study?
The benefits of PCI in patients with stable chronic ischemic heart disease are controversial, and there is frequent use of ad-hoc PCI without FFR guidance in Italy.
Does the use of physiologic guidance (FFR) and mandatory Heart Team assessment correlate with the rate of PCI and ad-hoc procedures for stable ischemic heart disease?
Observational
Yes
Does the use of physiologic guidance (FFR) and mandatory Heart Team assessment correlate with the rate of PCI and ad-hoc procedures for stable ischemic heart disease?
Answers are grounded in this paper and cite their sources.
Higher regional use of physiologic guidance (FFR) and mandatory Heart Team assessments are associated with lower rates of PCI and ad-hoc procedures for stable ischemic heart disease.
AIMS: Although the benefits of percutaneous coronary interventions (PCIs) in patients with stable chronic ischemic heart disease (SIHD) are controversial, a large number of PCIs are currently performed in SIHD patients, frequently after coronary angiography (ad-hoc procedures), without the use of fractional flow reserve (FFR) to identify patients most likely to benefit from PCI. METHODS: Assessment of regional variations in PCI for SIHD performed in Italy in 2017 and correlation of the regional number of PCI per million inhabitants with the use of FFR were performed using the data reported in the registry of the Italian Society of Interventional Cardiology (SICI-GISE) registry for the year 2017. RESULTS: PCI for SIHD accounted for 44.5% of all PCI performed in Italy with large variations among the Italian regions. There was a significant and inverse relationship between the use of FFR and the PCI number per million inhabitants performed for SIHD in the various Italian regions (P = 0.01). In the Veneto region, where local authorities mandated Heart Team reports to select the most appropriate treatment choice in multivessel disease patients, the rate of ad-hoc procedures was significantly lower than the national average. CONCLUSION: PCI for SIHD patients represent almost half of all procedures currently performed in Italy with regional variations inversely related to physiologic guidance use. The mandatory assessment by the Heart Team to select the most appropriate treatment choice in multivessel disease patients is associated with a significantly lower number of ad-hoc procedures.
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Servi et al. (2019) conducted an observational in Stable ischemic heart disease. Fractional flow reserve (FFR) use was evaluated on Correlation between FFR use and PCI number per million inhabitants for SIHD (p=0.01). Regional use of fractional flow reserve was significantly and inversely related to the number of PCIs performed per million inhabitants for stable ischemic heart disease in Italy (P=0.01).
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