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July 12, 2006Journal of the American Society of Nephrology

Risk for Progression to ESRD

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Key result

The risk for incident ESRD among US white individuals with stages 3 to 4 CKD was 2.5-fold greater compared with Norwegians, despite similar CKD prevalence.

Population

Norwegians and US white individuals with stages 3 to 4 chronic kidney disease (CKD)

Design

Editorial

Authors

HWHaimanot WasseWMWilliam McClellan

Discussion

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Member takes

Overview

May reflect healthcare access gaps in US CKD care; leaves open socioeconomic drivers of ESRD progression disparities.

Structured PICO

P
Population
Norwegians and US white individuals with stages 3 to 4 chronic kidney disease (CKD)
O
Outcome
Incident end-stage renal disease (ESRD)hard clinical

Main Result

Relative Risk: 2.5

Despite similar CKD prevalence, US white individuals have a 2.5-fold higher risk of progressing to ESRD compared to Norwegians, highlighting the potential impact of healthcare access and socioeconomic factors on disease progression.

Limitations

  • Potential misclassification of incident ESRD as a result of incomplete capture of cases
  • Misestimation of prevalent CKD attributable to the MDRD equation
  • Differences in survival rates or risk for progression to ESRD among individuals with the same degree of CKD
  • Potential misclassification of incident ESRD as a result of incomplete capture of incident ESRD cases because of differences in acceptance rates

Cite This Study

Wasse et al. (2006) conducted an editorial in Chronic kidney disease and ESRD. US white population vs. Norwegian population was evaluated on Incident ESRD among individuals with stages 3 to 4 CKD (2.5-fold greater risk). The risk for incident ESRD among US white individuals with stages 3 to 4 CKD was 2.5-fold greater compared with Norwegians, despite similar CKD prevalence.

synapsesocial.com/papers/6aaf94fda5af4fa898d07ac7https://doi.org/10.1681/asn.2006060632
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1International Comparison of the Relationship of Chronic Kidney Disease Prevalence and ESRD Risk2006 · 697 citations
  2. 2Racial disparities in chronic kidney disease: Need for attention2024
  3. 3Web Surveillance for CKD2012 · 7 citations
  4. 4Kidney Failure Stabilizes after a Two-Decade Increase2006 · 23 citations
  5. 5Overview2004 · 126 citations