Key result
CSF tau levels strongly correlate with the alpha/delta global field power ratio in AD.
Why the study?
The relationship between cerebrospinal fluid tau levels and EEG slowing in Alzheimer's disease and cognitive decline was unclear.
Cross-Sectional (n=40)
Effect estimate: r = 0.65
p-value: p=0.01
In Alzheimer's disease patients, there is a significant correlation between CSF tau levels and EEG slowing, particularly in those with shorter illness duration.
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Suggests tau-EEG link in AD; leaves open validation as combined biomarker in larger prospective studies.
Jelić et al. (1998) conducted a cross-sectional in Alzheimer's disease and cognitive decline (n=40). Cerebrospinal fluid (CSF) tau levels was evaluated on Correlation between CSF tau levels and ratio of alpha/delta global field power (r = 0.65, p=0.01). Cerebrospinal fluid tau levels positively correlated with the ratio of alpha/delta global field power in patients with Alzheimer's disease (r = 0.65, p = 0.01).
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