Key result
Concordant CMR and FDG PET/CT in myocarditis linked to ~261% higher MACE risk vs discordant findings.
Why the study?
Do concordant FDG PET/CT and CMR findings predict major adverse cardiovascular events in patients with known or suspected myocarditis?
Population
100 patients with known or suspected myocarditis, mean age 59±13 years, 74% male, LVEF 51±13%.
Comparison
Concordant imaging findings vs Discordant imaging findings
Design
Cohort
Follow-up
1 year
Authors
Loading...
Concordant FDG PET/CT and CMR findings may refine myocarditis risk stratification; hypothesis-generating and requires prospective validation before guiding decisions.
Cohort (n=100)
No
Do concordant FDG PET/CT and CMR findings predict major adverse cardiovascular events in patients with known or suspected myocarditis?
Hazard Ratio: 3.61 (95% CI 1.14–11.39)
p-value: p=0.028
Concordant findings of focal LGE on CMR and FDG uptake on PET/CT are associated with a significantly increased risk of major adverse cardiovascular events at one year in patients with known or suspected myocarditis.
Rojulpote et al. (2026) conducted a cohort in Known or suspected myocarditis (n=100). Concordant CMR and FDG PET/CT imaging findings vs. Discordant imaging findings was evaluated on Major adverse cardiovascular event (MACE), a composite of heart failure hospitalization, sustained ventricular tachycardia/fibrillation, VT ablation, LVAD placement, cardiac transplant, and death at one-year (aHR 3.61, 95% CI 1.14-11.39, p=0.028). Concordant CMR and FDG PET/CT findings in myocarditis patients were associated with a higher risk of MACE at one year compared to discordant findings (aHR 3.61; 95% CI 1.14-11.39; p=0.028).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: