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The reaction of (ZS.4_R)-2-alkyl-N-methyl-4-phenyl-l,3oxazolldlnes (&-c) wlth Grignard reagent gave (1_R,lV_R)-form compounds ( g -2 ) as the malor product.On the contrary, the reactlon of &-c wlth organotitanlum reagent gave (1S,l'?)-form compounds -
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Takahashi et al. (1988) studied this question.
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