Key result
High perceived stress before PCI linked to ~548% greater short-term MACE risk.
Why the study?
The impact of perceived stress levels on the prognosis of patients undergoing PCI was not well established.
Does high perceived stress increase the risk of major adverse cardiovascular events in patients undergoing initial percutaneous coronary intervention?
Cohort (n=339)
Yes
Does high perceived stress increase the risk of major adverse cardiovascular events in patients undergoing initial percutaneous coronary intervention?
High perceived stress at baseline is a strong independent predictor of short-term major adverse cardiovascular events in patients undergoing initial PCI.
Answers are grounded in this paper and cite their sources.
High perceived stress may flag elevated short-term MACE risk after PCI; hypothesis-generating and requires prospective confirmation before practice change.
OBJECTIVE: To assess the impact of perceived stress levels in patients undergoing percutaneous coronary intervention (PCI) on the occurrence of major adverse cardiovascular events (MACEs) within a 6-month follow-up period postprocedure. METHODS: A cohort of 339 hospitalized patients with coronary heart disease undergoing initial PCI was prospectively enrolled in the Department of Cardiology at two branches of Zhongda Hospital Affiliated to Southeast University between January 2022 and July 2022. Baseline data including demographic and clinical characteristics, along with the Chinese Perceived Stress Scale (CPSS), were collected. The occurrence of MACE was evaluated at 3 and 6 months post-PCI. Kaplan-Meier survival analysis and Cox regression models were engaged to analyze the relationship between perceived stress and MACE within 6 months after PCI. RESULTS: MACE occurred in 16.22% (55/339) of patients during the 6 following months. High CPSS at baseline was significantly associated with an increasing risk of short-term MACE occurrence (HR: 6.48, 95% confidence interval: 2.98-14.11, P < 0.05). CONCLUSION: High perceived stress during the baseline period after PCI was significantly correlated with increased incidence of MACE within 6 months postprocedure. The perceived stress level could help to identify patients undergoing PCI at heightened risk of short-term MACE.
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Shi et al. (2024) conducted a cohort in Coronary heart disease undergoing initial PCI (n=339). High perceived stress was evaluated on Major adverse cardiovascular events (MACEs) (HR 6.48, 95% CI 2.98-14.11, p=< 0.05). High perceived stress at baseline in patients undergoing PCI was significantly associated with an increased risk of short-term MACE (HR 6.48; 95% CI 2.98-14.11; P<0.05).
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