Key result
Renal disease linked to ~481% higher odds of prolonged hospital stay in preeclampsia.
Why the study?
Correlates of prolonged length of stay in women hospitalized for preeclampsia/eclampsia in Texas were not well defined.
Cohort (n=21,203)
Yes
Odds Ratio: 5.81 (95% CI 3.97–8.5)
In women hospitalized for preeclampsia, the presence of renal disease is the strongest risk factor for a prolonged length of stay.
Renal disease identifies preeclampsia patients at highest prolonged-stay risk; hypothesis-generating for risk stratification and requires prospective validation.
OBJECTIVES: To identify correlates of a prolonged length of stay (PLOS) in women hospitalized for preeclampsia/eclampsia in Texas, USA. METHODS: Statewide hospital data were obtained, and the records of women who were discharged in 2004 and/or 2005 with a principal discharge diagnosis of preeclampsia or eclampsia were extracted using ICD-9-CM codes. PLOS was defined as a stay greater than 5 days. Odds ratios (OR) for PLOS were calculated. Generalized estimating equations were used to account for a small group of women who were hospitalized multiple times during the study period for preeclampsia. A total of 21,203 records were analyzed. RESULTS: The crude incidence of PLOS was 17.5%. Advancing maternal age was positively associated with PLOS: for every 10-year increase, there was a 20% increase in the odds of PLOS (adjusted OR = 1.20,95% confidence interval (CI): 1.13, 1.28). The strongest risk factor for PLOS was the presence of renal disease: adjusted OR 5.81 (95% CI: 3.97, 8.50). Protective factors included Medicaid beneficiary status, and being admitted from the emergency department. CONCLUSIONS: The strongest correlate of PLOS in a large cohort of women hospitalized for preeclampsia was the presence of renal disease.
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Mulla et al. (2009) conducted a cohort in Preeclampsia/eclampsia (n=21,203). Renal disease vs. Absence of renal disease was evaluated on Prolonged length of stay (PLOS) > 5 days (OR 5.81, 95% CI 3.97-8.50). The presence of renal disease was the strongest risk factor for a prolonged length of stay in women hospitalized for preeclampsia (adjusted OR 5.81; 95% CI 3.97-8.50).
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