Key result
Female sex is linked to ~4-fold higher adolescent PE hospitalization rates compared to males.
Why the study?
Detailed description of the prevalence and sex-specific differences of pulmonary embolism in hospitalized young patients in Germany was not previously possible before DRG introduction in 2003.
Population
Hospitalized patients aged 10-40 years with pulmonary embolism in Germany in 2005-2007
Comparison
Females vs males in pulmonary embolism incidence and comorbidity
Design
Observational analysis of federal statistical office data
Authors
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May prompt earlier PE evaluation in adolescent females; leaves open causal mechanisms and targeted prevention beyond pregnancy.
Observational
Yes
Young females experience a significantly higher incidence of pulmonary embolism starting at early adolescence compared to males, a difference that resolves by the early thirties and is not fully explained by pregnancy.
Moysidis et al. (2010) conducted an observational in Pulmonary embolism. Female sex vs. Male sex was evaluated on Incidence of hospitalization for pulmonary embolism. Female sex is associated with a sharp increase in hospitalization for pulmonary embolism beginning at age 12-13 years compared to males, with the highest female-to-male ratio (3 to 5) at 16-17 years.
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