Key result
Elevated troponins and natriuretic peptides are linked to increased mortality in acute pulmonary embolism.
Why the study?
The prognostic role of cardiac troponins and natriuretic peptides in acute pulmonary embolism has been increasingly recognized, warranting comprehensive risk stratification approaches.
Do biomarkers (troponins, natriuretic peptides) and echocardiography provide prognostic information in patients with acute pulmonary embolism?
Do biomarkers (troponins, natriuretic peptides) and echocardiography provide prognostic information in patients with acute pulmonary embolism?
Cardiac troponins and natriuretic peptides are valuable biomarkers for prognostic risk stratification in patients with acute pulmonary embolism.
Supports troponin/NT-proBNP for PE risk stratification; leaves open integration into management algorithms.
ince the initial observation that elevated cardiac troponin T levels are closely associated with mortality in acute pulmonary embolism, 1 several reports have confirmed the prognostic role of cardiac troponins in this setting.2,3 More recently, yet another group of biomarkers, the natriuretic peptides B-type natriuretic peptide (BNP) and N-terminal-pro-B-type natriuretic peptide (NT-proBNP), emerged to confer additional prognostic information.4 -7
No takes yet. Share an insight, caveat, or question.
Giannitsis et al. (2005) conducted a review in acute pulmonary embolism. Biomarkers (cardiac troponins, BNP, NT-proBNP) was evaluated on mortality and prognosis. Elevated cardiac troponins and natriuretic peptides (BNP and NT-proBNP) are associated with mortality and provide prognostic information in acute pulmonary embolism.