Key result
CMRI identifies characteristic INVM features including prominent trabeculations across left, right, and biventricular cases.
Why the study?
The cardiac magnetic resonance imaging features of isolated noncompaction of ventricular myocardium have not been comprehensively summarized.
Observational (n=11)
Cardiac MRI provides characteristic diagnostic features for isolated noncompaction of ventricular myocardium, including prominent trabeculations and increased noncompacted to compacted myocardium ratio.
May aid INVM diagnosis via CMRI in select cases; leaves open prospective validation of diagnostic criteria.
OBJECTIVE: To retrospectively summarize the cardiac magnetic resonance imaging (CMRI) findings of isolated noncompaction of ventricular myocardium (INVM). MATERIALS AND METHODS: Eleven patients (M:F = 9:2; mean age, 35 years) were evaluated. Steady-state free precession (SSFP), fast spin echo (SE) sequence, SSFP cine imaging, and delayed enhanced inversion recovery spoiled gradient echo (IR-SPGR) sequence were used for showing abnormal myocardium, measuring ratio of noncompacted/compacted myocardium layers (NC/C ratio), and detecting myocardial viability. The left ventricle was divided into nine segments and a NC/C ratio > 2.3 in diastole was used as cutoff value in diagnosing left INVM. The right ventricle was assessed qualitatively. RESULTS: Cardiac MRI indicated left INVM in seven patients, right INVM in one patient and biventricle INVM in three patients. Characteristic CMRI changes included prominent trabeculations, deep intertrabecular recesses and an increase in the NC/C ratio. The most frequently involved segments was left ventricular apex. Three patients had abnormal high signals within the trabecular structures on SE T2 weighted image. One ventricular aneurysm and one apical thrombus were also observed. Delayed enhancement was seen in six of nine patients with subendocardial and transmural patterns. CONCLUSION: There are CMRI features that might be characteristic for INVM.
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Yun et al. (2011) conducted an observational in Isolated noncompaction of ventricular myocardium (INVM) (n=11). Cardiac magnetic resonance imaging (CMRI) was evaluated on CMRI findings of INVM. Cardiac magnetic resonance imaging identified left INVM in 7 patients, right INVM in 1, and biventricular INVM in 3, with characteristic features including prominent trabeculations.
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