Key result
Low-dose intrathrombus streptokinase plus angioplasty yields ~88% success treating unilateral iliac artery occlusions.
Why the study?
Management of chronic and acute unilateral iliac artery occlusions with intrathrombus streptokinase infusion combined with angioplasty was evaluated for safety and efficacy.
Does intrathrombus streptokinase infusion combined with angioplasty successfully treat unilateral iliac artery occlusion?
Case Report (n=8)
Does intrathrombus streptokinase infusion combined with angioplasty successfully treat unilateral iliac artery occlusion?
Intrathrombus streptokinase infusion combined with angioplasty is a feasible and potentially safer approach for treating unilateral iliac artery occlusions.
May support combined thrombolysis and angioplasty for iliac occlusions; hypothesis-generating and should not yet change practice.
Chronic and acute unilateral iliac artery occlusions were successfully treated in 7 of 8 patients using low-dose intrathrombus streptokinase infusions ranging from 6 to 43 hours in combination with percutaneous transluminal angioplasty. Angioplasty of an underlying stenosis was performed as soon as clot lysis was maximal and an underlying stenosis was demonstrated. Long-term follow-up to date has been excellent. This approach to unilateral iliac occlusion appears to be safer than previously reported angioplasty of iliac artery occlusion.
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Auster et al. (1984) conducted a case report in Chronic and acute unilateral iliac artery occlusions (n=8). Intrathrombus streptokinase infusion and percutaneous transluminal angioplasty was evaluated on Successful treatment. Low-dose intrathrombus streptokinase infusion combined with angioplasty successfully treated unilateral iliac artery occlusions in 7 of 8 patients (87.5%).
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