Key result
18F-NaF PET/CT imaging detects residual right ventricular osteosarcoma metastases after debulking surgery.
Why the study?
Cardiac metastasis from osteosarcoma is rare and imaging characteristics using 18F-NaF PET/CT are not well described.
Case Report (n=1)
18F-NaF PET/CT may be useful for detecting residual cardiac metastasis from osteosarcoma.
May support 18F-NaF PET/CT for residual cardiac osteosarcoma metastases; hypothesis-generating case report requiring prospective validation.
Osteosarcomas are aggressive with a high incidence of recurrence and metastasis. Cardiac osteosarcoma metastasis is rare. We described a 17-year-old boy who had right distal femoral osteosarcoma with lung metastases. During follow-up, right ventricular (RV) metastasis was noted and confirmed by histopathological examination of the surgical specimen. F-NaF PET/CT was then arranged 1 month after debulking surgery for residual tumor survey. The images showed intense F-NaF uptake at RV region, suggestive of residual cardiac metastases.
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Chou et al. (2016) conducted a case report in Cardiac metastasis from osteosarcoma (n=1). 18F-NaF PET/CT was evaluated on Detection of residual cardiac metastases. 18F-NaF PET/CT imaging successfully identified intense uptake in the right ventricular region, suggestive of residual cardiac metastases from osteosarcoma after debulking surgery.
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