Key result
Intrathecal morphine addition to bupivacaine for elective cesarean section yields no reported results.
RCT (n=34)
Randomly divided into 2 groups
Answers are grounded in this paper and cite their sources.
Insufficient evidence from this small unreported trial to guide practice; leaves open intrathecal morphine efficacy in cesarean anesthesia.
Thirty-four patients scheduled for elective repeat cesarean section at term under spinal anesthesia were randomly divided into 2 groups. All patients received hyperbaric 0.75% bupivacaine with the addition of either 0.2 ml of saline or 0.2 mg of preservative-free morphine. Routine management of the parturient with spinal anesthesia was carried out in all patients. Among the variables monitored were respiratory rate, noninvasive oxygen saturation, hemodynamic changes, state of consciousness, extent and adequacy of intra-operative analgesia, duration of postoperative analgesia, postoperative narcotic requirements, and neonatal condition at birth.
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Abouleish et al. (1988) conducted an RCT in Elective repeat cesarean section (n=34). Intrathecal morphine vs. 0.2 ml saline added to hyperbaric 0.75% bupivacaine was evaluated. A randomized trial of 34 patients evaluated the addition of intrathecal morphine to bupivacaine for elective cesarean section, though no results are reported in the abstract.
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