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December 1, 2016The American Surgeon

Active Mental Illnesses Adversely Affect Surgical Outcomes

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Key result

Active mental illness linked to ~292% higher readmission rates and more ER visits after elective surgery.

  • P=0.009
  • n=183

Why the study?

Comparable data on the impact of depression, anxiety, PTSD, and substance abuse on outcomes after elective general surgery were lacking.

Does active mental illness increase the risk of 30-day complications, readmissions, and ER visits in patients undergoing elective general surgery?

Population

183 consecutive patients undergoing elective general surgery at a single tertiary hospital

Comparison

Patients with active mental illness vs without mental illness

Design

Cohort study

Follow-up

30 days

Authors

DLDavid S. LeeWashington University in St. LouisLMLaura MarshMichael E. DeBakey VA Medical CenterMGMauro A. Garcia-AltieriMichael E. DeBakey VA Medical Center

Discussion

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Implication

May warrant mental health screening before elective surgery; hypothesis-generating and requires prospective confirmation before changing practice.

Study Design

Type

Cohort (n=183)

Multicenter

No

Structured PICO

Does active mental illness increase the risk of 30-day complications, readmissions, and ER visits in patients undergoing elective general surgery?

P
Population
183 consecutive patients undergoing elective general surgery procedures at a single tertiary hospital, assessed for 30-day outcomes.
E
Exposure
Presence of active mental illness (AMI) including depression, anxiety, PTSD, and/or substance abuse at the time of surgery
C
Comparator
Without a mental illness (WAMI)
O
Outcome
30-day complications, readmissions, and emergency room (ER) visitshard clinical

Main Result

Absolute Event Rate: 14.5% vs 3.7%

p-value: p=0.009

Active mental illnesses such as depression, anxiety, PTSD, and substance abuse are associated with significantly higher rates of 30-day readmissions and ER visits following elective general surgery.

Cite This Study

Lee et al. (2016) conducted a cohort in Elective general surgery (n=183). Active mental illness (depression, anxiety, PTSD, and/or substance abuse) vs. Without a mental illness was evaluated on Readmissions (p=0.009). Active mental illness in patients undergoing elective general surgery was associated with higher rates of readmissions (14.5% vs 3.7%, P=0.009) and ER visits (19.7% vs 8.4%, P=0.025).

synapsesocial.com/papers/6ab096ae82dff9e0929597a1https://doi.org/10.1177/000313481608201233
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Patients With Depression Are Less Likely to Follow Recommendations to Reduce Cardiac Risk During Recovery From a Myocardial Infarction2000 · 717 citations
  2. 2Depression Is Associated With Increased Mortality 10 Years After Coronary Artery Bypass Surgery2010 · 115 citations
  3. 3Anxiety Predicts Mortality and Morbidity After Coronary Artery and Valve Surgery—A 4-Year Follow-Up Study2007 · 207 citations
  4. 4Depressive Symptoms and Mortality in Patients After Kidney Transplantation: A Prospective Prevalent Cohort Study2010 · 122 citations
  5. 5Psychiatric Disorders Among Bariatric Surgery Candidates: Relationship to Obesity and Functional Health Status2007 · 587 citations