Key result
A single hemodialysis absence is linked to ~120% higher 30-day mortality and increased hospitalization risk.
Why the study?
The rate of missed hemodialysis treatments and the association between treatment nonadherence and clinical outcomes were not well characterized.
Does treatment nonadherence increase the risk of hospitalization and death in hemodialysis patients?
Observational
Does treatment nonadherence increase the risk of hospitalization and death in hemodialysis patients?
Relative Risk: 2.2
Treatment nonadherence is common among hemodialysis patients and is strongly associated with increased short-term risks of hospitalization and death.
OBJECTIVE: The aim of this study was to determine the rate of missed treatments among hemodialysis (HD) patients, and the association between treatment nonadherence and clinical outcomes. DATA SOURCE: The data used in this study were based on electronic medical records and Medicare claims. STUDY DESIGN: This is a retrospective, observational study. PRINCIPAL FINDINGS: HD patients miss 9.9% of all treatments. Approximately half of the missed treatments are due to observable medical events, predominantly hospitalizations, while half result from nonadherence ("absence"). A single absence is associated with a 1.4-fold greater risk of hospitalization, and a 2.2-fold greater risk of death in the subsequent 30 days. CONCLUSION: Treatment nonadherence is common among HD patients and is associated with adverse outcomes. Interventions that improve adherence may improve patient health and reduce costs.
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Gray et al. (2017) conducted an observational in Hemodialysis. Treatment nonadherence (single absence) vs. Adherence (no absence) was evaluated on Hospitalization and death in the subsequent 30 days (1.4-fold greater risk of hospitalization, 2.2-fold greater risk of death). A single hemodialysis absence was associated with a 1.4-fold greater risk of hospitalization and a 2.2-fold greater risk of death in the subsequent 30 days.
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