Recently reported syntheses of 3(5)-aminopyrazoles, 4-aminopyrazoles, and 1-aminopyrazoles as well as of diaminopyrazoles and their general pattern of reactivity towards mono-and bidentate electrophiles have been surveyed.Emphasis has also been laid on techniques for ascertaining the site selectivity in reactions with electrophiles, including single crystal X-ray structure analysis, 1 H-15 N HMBC, and NOE intensity difference experiments as well as other modern 2D NMR techniques.Some thermally induced cycloadditions have also been treated.
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Anwar et al. (2009) studied this question.
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