Key result
Arterial pH <7.0 and lactate ≥5.0 linked to ~620% higher 5-day mortality after OHCA.
Why the study?
There is a lack of valid parameters for the prediction of survival after out-of-hospital cardiac arrest.
Do arterial blood gas parameters predict mortality in patients admitted after out-of-hospital cardiac arrest?
Population
170 patients admitted after out-of-hospital cardiac arrest resuscitation between 2008 and 2013
Comparison
Arterial blood gas parameters including pH < 7.0 and lactate ≥ 5.0 mmol/L
Design
Retrospective observational study
Follow-up
5 days
Authors
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These thresholds may refine early risk stratification after OHCA; hypothesis-generating and requires prospective validation before guiding care.
Observational (n=170)
No
Do arterial blood gas parameters predict mortality in patients admitted after out-of-hospital cardiac arrest?
Odds Ratio: 7.2 (95% CI 3.11–16.69)
p-value: p=< 0.001
Arterial blood gas parameters, specifically pH < 7.0 and lactate ≥ 5.0 mmol/L, are strong independent predictors of early mortality after out-of-hospital cardiac arrest and can contribute to multimodal prognostication.
Auenmueller et al. (2017) conducted an observational in Out-of-hospital cardiac arrest (n=170). Arterial blood gas parameters (pH < 7.0 and lactate ≥ 5.0 mmol/L) vs. Normal or less deranged arterial blood gas parameters was evaluated on Mortality within the first 5 days after hospital admission (OR 7.20, 95% CI 3.11-16.69, p=< 0.001). An arterial pH < 7.0 (OR 7.20; 95% CI 3.11-16.69) and lactate ≥ 5.0 mmol/L (OR 6.79; 95% CI 2.77-16.66) were strongly associated with 5-day mortality after out-of-hospital cardiac arrest.
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