Key result
Turbulence slope modestly correlates with the HRV LF/HF ratio in structurally normal hearts.
Why the study?
The relationship between heart rate turbulence and heart rate variability parameters in adults with structurally normal hearts was not established.
Cross-Sectional (n=61)
No
Effect estimate: r=0.35
p-value: p=0.006
Turbulence slope correlates significantly with heart rate variability parameters in adults with structurally normal hearts, suggesting it reflects overall cardiac autonomic tone.
Ts correlates with select HRV indices in normal hearts; leaves open independent prognostic utility and requires prospective validation.
Background and Objectives:Heart rate variability (HRV) illustrates the autonomic integration of the heart. Depressed HRV has been proven to be associated with an increased risk of cardiac death, whereas heart rate turbulence (HRT) is believed to reflect baroreflex sensitivity and it was recently introduced as another noninvasive tool for risk stratification. The aim of this study was to determine the relationship between the HRT and HRV parameters in Korean adults with a structurally normal heart. Subjects and Methods:We studied 61 adults (males: 31) who showed ventricular premature complexes on 24 hour Holter recording and who were found to have normal hearts on full noninvasive investigation. We calculated the mean heart rate (RR interval), the number of VPBs, the timeand frequency-domain HRV parameters and two HRT parameters: turbulence onset (To) and turbulence slope (Ts). Results:Ts showed a strong correlation with the HRV parameters (LF/HF ratio: r=0.35, p=0.006; VLF: r=0.32, p=0.013; LF: r=0.27, p=0.035; SDNN: r=0.28, p=0.029; SDANN: r=0.32, p=0.012), but To showed no significant correlation with the HRV parameters. Conclusion:The HRT parameters, and especially Ts, correlate strongly with the HRV parameters; therefore, Ts should be considered as a parameter that reflects the overall cardiac autonomic tone. (Korean Circulation J 2006;36:126-132)
No takes yet. Share an insight, caveat, or question.
Yoon et al. (2006) conducted a cross-sectional in Structurally normal heart with ventricular premature complexes (n=61). Heart rate turbulence (HRT) was evaluated on Correlation between turbulence slope (Ts) and LF/HF ratio (r=0.35, p=0.006). In Korean adults with structurally normal hearts, the heart rate turbulence parameter turbulence slope (Ts) correlated significantly with the heart rate variability LF/HF ratio (r=0.35, p=0.006).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: