Time to first shock and clinical outcome in patients receiving an automatic implantable cardioverter-defibrillator
Key result
Lower EF predicts higher mortality in AICD patients but not the risk of first shock.
- n=60
Why the study?
The relation between time to first shock and clinical outcome in patients with an automatic implantable cardioverter-defibrillator was studied to better understand prognostic implications.
Does the time to first shock predict clinical outcome in patients receiving an automatic implantable cardioverter-defibrillator?
Population
60 patients who received an automatic implantable cardioverter-defibrillator from August 1983 through May 1988
Comparison
Patients with one or more shocks vs patients with no shocks
Design
Cohort study
Authors
Discussion
Loading...
Member takes
Implication
Lower EF does not predict first AICD shock despite linking to mortality; leaves open identification of better risk stratifiers.
Study Design
Type
Cohort (n=60)
Structured PICO
Does the time to first shock predict clinical outcome in patients receiving an automatic implantable cardioverter-defibrillator?
P
Population
60 patients (mean age 64, 18% female) who received an automatic implantable cardioverter-defibrillator, followed to assess the relation between time to first shock and clinical outcome.
E
Exposure
Automatic implantable cardioverter-defibrillator (AICD)
O
Outcome
Clinical outcome (death) in relation to time to first shockhard clinical
Early appropriate shocks (within 3 months) in AICD patients are associated with subsequent mortality, though death is often delayed.
Cite This Study
Myerburg et al. (1989) conducted a cohort in Patients receiving an automatic implantable cardioverter-defibrillator (n=60). AICD shocks vs. No shocks was evaluated on Clinical outcome (death). Among patients receiving an AICD, 63% experienced shocks, and lower ejection fraction predicted mortality (25% vs 35%, p<0.02) but did not distinguish the risk of receiving a first shock.