Key result
Higher Prognostic Nutritional Index correlates with greater coronary collateral development.
Why the study?
The association between Prognostic Nutritional Index and coronary collateral development in patients with stable coronary artery disease was not established.
Is the Prognostic Nutritional Index associated with coronary collateral development in patients with chronic total occlusion?
Observational (n=172)
Is the Prognostic Nutritional Index associated with coronary collateral development in patients with chronic total occlusion?
The Prognostic Nutritional Index, a simple immunonutritional parameter, independently predicts the development of coronary collaterals in patients with chronic total occlusion.
Answers are grounded in this paper and cite their sources.
PNI may aid collateral risk stratification in CTO; leaves open whether nutritional optimization improves development.
BACKGROUND: Nutritional status is a predictor of the prognosis of cardiovascular diseases. The association between the Prognostic Nutritional Index (PNI), which is an immunonutritional parameter, and cardiovascular diseases has been extensively studied in the literature. OBJECTIVES: The aim of this study was to investigate whether PNI is associated with coronary collateral development. METHODS: This retrospective study included 172 patients with chronic total occlusion. The patients were diagnosed with stable coronary artery disease, and all patients underwent coronary angiography. PNI was calculated using serum albumin level and lymphocyte count. Collateral circulation was classified according to Rentrop grade. RESULTS: There was a positive correlation between PNI and Rentrop grade (r = 0.168, p = 0.026) and a negative correlation between C-reactive protein and PNI (r = -0.353, p < 0.001). Multivariate logistic regression analysis showed that uric acid and PNI were independent predictors of Rentrop grade (p = 0.008 and p = 0.037, respectively). CONCLUSIONS: This study showed that PNI, which can easily be calculated using serum albumin level and lymphocyte count, was a predictor of coronary collateral development in terms of Rentrop grade.
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Akbuğa et al. (2022) conducted an observational in Chronic total occlusion (n=172). Prognostic Nutritional Index was evaluated on Coronary collateral development (Rentrop grade) (r = 0.168, p=0.026). The Prognostic Nutritional Index was positively correlated with Rentrop grade (r = 0.168, p = 0.026) and emerged as an independent predictor of coronary collateral development (p = 0.037).
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