Key result
Perceived poor prognosis in nursing home residents is linked to discontinuing beta-blockers ~34 days earlier.
Why the study?
Given the limited life expectancy of nursing home residents, the harms of continuing beta-blockers may outweigh clinical benefits, but patterns of discontinuation are not well described.
Cohort (n=88,284)
Absolute Event Rate: 245% vs 279%
p-value: p=< 0.0001
Beta-blockers are frequently continued until the end of life in nursing home residents, though discontinuation occurs earlier when clinicians perceive a limited life expectancy.
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May inform deprescribing decisions near end of life in nursing homes; leaves open effects on outcomes.
Lee et al. (2021) conducted a cohort in Nursing home residents at end of life (n=88,284). Perceived poor prognosis vs. Without perceived poor prognosis was evaluated on Mean time until beta-blocker discontinuation (days) (p=< 0.0001). Nursing home residents with a perceived poor prognosis discontinued beta-blockers earlier than those without such prognosis (mean 245 vs 279 days; p<0.0001).
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