Key result
Left ventricular assist system support reduced right ventricular afterload, allowing all 8 patients (100%) to survive support and cardiac transplantation.
Why the study?
The effects of left ventricular assist system support on right ventricular performance during clinical left ventricular assistance were evaluated.
Does left ventricular assist system (LVAS) support maintain adequate right ventricular function in patients bridged to cardiac transplantation?
Observational (n=8)
Does left ventricular assist system (LVAS) support maintain adequate right ventricular function in patients bridged to cardiac transplantation?
Answers are grounded in this paper and cite their sources.
LVAS support reduces RV afterload, allowing even patients with marginal RV function to survive as a bridge to cardiac transplantation.
Hemodynamic and mechanical parameters of right ventricular (RV) performance were measured in eight patients undergoing left ventricular (LV) assistance as a bridge to cardiac transplantation. All patients, even those with impaired RV performance, survived support and transplantation. The reduction of LV afterload produced by the left ventricular assist system (LVAS) results in RV afterload reduction, which permits even the marginal RV to function adequately during LVAS support.
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Kormos et al. (1989) conducted an observational in Heart failure requiring left ventricular assistance (n=8). Left ventricular assist system (LVAS) was evaluated on Survival of support and transplantation. Left ventricular assist system support reduced right ventricular afterload, allowing all 8 patients (100%) to survive support and cardiac transplantation.
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