Key result
Peritoneal dialysis linked to ~7% higher hospitalization risk and increased in-hospital death versus hemodialysis.
Why the study?
High rates of hospitalization in dialysis patients impose an increasing healthcare burden, and comparative data on hospital admissions and causes between hemodialysis and peritoneal dialysis patients are needed.
Does peritoneal dialysis compared to hemodialysis affect the risk of hospital admission and in-hospital death in patients starting maintenance dialysis?
Population
8902 patients starting maintenance dialysis in Sweden between 2006 and 2016
Comparison
Peritoneal dialysis vs hemodialysis
Design
Observational study
Follow-up
2 years
Authors
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Should not alter initial dialysis modality selection; observational data leave open residual confounding and need for randomized confirmation.
Observational (n=8,902)
Yes
Does peritoneal dialysis compared to hemodialysis affect the risk of hospital admission and in-hospital death in patients starting maintenance dialysis?
Hazard Ratio: 1.07 (95% CI 1.01–1.13)
Patients starting peritoneal dialysis have a slightly higher risk of hospitalization, longer hospital stays, and higher in-hospital mortality compared to those starting hemodialysis, with cardiovascular events and infections driving admissions.
Xu et al. (2021) conducted an observational in Maintenance dialysis (n=8,902). Peritoneal dialysis (PD) vs. Hemodialysis (HD) was evaluated on Hospital admission (HR 1.07, 95% CI 1.01-1.13). Compared with hemodialysis, patients on peritoneal dialysis had a higher risk of hospitalization (HR 1.07; 95% CI 1.01-1.13) and in-hospital death (HR 1.18; 95% CI 1.03-1.37).
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