Key result
Hemodialysis linked to ~25% lower hospitalization risk versus peritoneal dialysis in children.
Why the study?
Children receiving kidney replacement therapy frequently face complications resulting in recurrent hospitalizations, motivating a comparison of hospitalization rates and causes between chronic peritoneal dialysis and hemodialysis.
Does hemodialysis reduce the risk of hospitalization compared to peritoneal dialysis in children on chronic kidney replacement therapy?
Population
847 children (< 18 years) on chronic PD or HD
Comparison
Chronic peritoneal dialysis vs hemodialysis
Design
Nationwide retrospective observational registry study
Authors
Loading...
Should not yet change pediatric dialysis selection; leaves open whether hemodialysis truly lowers hospitalization versus peritoneal dialysis.
Observational (n=847)
Yes
Does hemodialysis reduce the risk of hospitalization compared to peritoneal dialysis in children on chronic kidney replacement therapy?
Effect estimate: aHR 0.75 (95% CI 0.65-0.87)
In children on chronic dialysis, hemodialysis is associated with a significantly lower risk of hospitalization over time compared to peritoneal dialysis.
Spagnol et al. (2026) conducted an observational in Kidney failure requiring chronic dialysis (n=847). Hemodialysis (HD) vs. Peritoneal dialysis (PD) was evaluated on Risk of hospitalization (aHR 0.75, 95% CI 0.65-0.87). Hemodialysis was associated with a lower risk of hospitalization compared to peritoneal dialysis in children on chronic dialysis (aHR 0.75; 95% CI 0.65-0.87).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: