Key result
Chronic hemodialysis initiation is linked to a ~295% increase in annual hospitalizations.
Why the study?
Does the initiation of chronic hemodialysis change the rate and length of hospitalizations in patients with end-stage renal disease?
Population
392 patients on chronic hemodialysis, 98% men, 59% diabetic, mean age 66.3 ± 11.2 years at the onset of HD…
Comparison
Chronic hemodialysis period vs Pre-hemodialysis period
Design
Cohort
Follow-up
Pre-HD period 60.0 ± 42.9 months; HD period 32.5 ± 25.9…
Authors
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May warrant closer post-initiation monitoring in ESRD; leaves open whether hemodialysis drives excess hospitalizations versus reflecting disease progression.
Cohort (n=392)
No
Does the initiation of chronic hemodialysis change the rate and length of hospitalizations in patients with end-stage renal disease?
Absolute Event Rate: 2.198% vs 0.557%
p-value: p=<0.001
The initiation of chronic hemodialysis is associated with a significant increase in both the rate and length of hospitalizations for all causes, including cardiac and HD-specific conditions.
Kassam et al. (2011) conducted a cohort in Chronic hemodialysis (n=392). Initiation of chronic hemodialysis vs. Pre-hemodialysis period was evaluated on Annual rate of hospitalizations for all causes (admissions/patient-year) (p=<0.001). Initiation of chronic hemodialysis was associated with a significant increase in the annual rate of hospitalizations from 0.557 to 2.198 admissions per patient-year (P<0.001).
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